Biomechanics of the spine is altered by the implantation of spinal devices used to stabilize the segment [ 29 ]. Along with many devices currently available in the market to treat spinal disorders, many new designs are also being developed in the hope to improve clinical outcomes. It is essential to evaluate their biomechanical efficacy among other issues, prior to clinical use [ 30 ]. The spinal implants can be evaluated by comparing the stability of the construct to the intact spine stability and/or stability provided by a predicate device. The biomechanical effects of decompression and stabilization provided by implants can be assessed using in vitro studies [ 31 , 32 ]. In vitro studies involving ligamentous spine specimens from human cadaver or other species like sheep, calf, and rabbit are carried out using standard test protocols [ 30 ]. Finite element analysis (FEA) in spine biomechanics is very helpful to perform the structural analysis of bone and bone implant composites of complicated geometry. Since it is difficult to get all the parameters from experimental studies, finite element models can be used to address the remaining issues [ 33 , 34 ]. Thus, in vitro and FE-based biomechanical studies provide valuable information on implants safety and effectiveness prior to their clinical use [ 30 ].