It should be noted that in theory if one was to consistently suppress your natural estrogen levels for a long period of time, this would negatively impact your health, including your cholesterol. Due to the ability of Letrozole- to inhibit estrogen so much, this should definitely be a concern to most users. However the research that has focused on the relationship between use of letrozole and cholesterol levels is rather inconsistent in it's findings. Many studies have concluded that the compound is detrimental to both a user's HDL and LDL cholesterol levels, while other research has found no link. Obviously individuals are best served to monitor their cholesterol while using any compound via blood tests however barring that, letrozole should simply not be run for extended periods of time if at all possible. Doing so could cause serious medical complications.
Along with the issues related to blood lipids is the fact that many users complain that their libido is dramatically reduced when using the compound. This is related to the fact that estrogen is partly responsible for the regulation of an individual's sex drive. Since Letrozole- is so potent it can often drive estrogen levels too low and this inhibits a user's libido. To avoid this users can lower dosages, but some anecdotally report that even extremely low doses of the drug can cause problems. If this is the case a less potent compound such as exemestane or anastrozole may be a more appropriate option.
What is it? An anabolic/androgenic steroid altered to produce better muscle-building properties, making it very popular for bodybuilders.
How it’s taken: Tablets or injections
Brand names: Winstrol, although that brand is no longer in production in the United States.
Legalities: Regulated as a Schedule III drug, meaning a valid prescription is required for possession.
What it does: Promotes muscle growth. In the past, it has been prescribed for patients with osteoporosis, growth deficiencies and hereditary angioedema, a disease that causes swelling.
Side effects/risks: Oily skin, acne and hair loss. More severe risks include liver damage, cardiovascular strain, mood changes and hardening of the arteries.
In the news: Canadian sprinter Ben Johnson was stripped of his 1988 Olympic gold medal after testing positive for stanozolol.